p egfr (Cell Signaling Technology Inc)
Structured Review

P Egfr, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 97/100, based on 4185 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/p+egfr/EGF+Receptor+Antibody/pmc12914112-62-65-66
Average 97 stars, based on 4185 article reviews
Images
1) Product Images from "MFAP2 promotes metastasis and drug resistance by regulating epithelial-to-mesenchymal transition through EGFR signaling pathway in colorectal cancer cells"
Article Title: MFAP2 promotes metastasis and drug resistance by regulating epithelial-to-mesenchymal transition through EGFR signaling pathway in colorectal cancer cells
Journal: Genes & Diseases
doi: 10.1016/j.gendis.2025.101800
Figure Legend Snippet: MFAP2 promotes epithelial–mesenchymal transition (EMT) through the EGFR-AKT-STAT3 signaling pathway in colorectal cancer (CRC) cells. (A, B) The top 20 enrichment signaling pathways regulated by MFAP2 knockdown. (C, D) VEGFR2 signaling pathway was enriched in the MFAP2 knockdown cells, shown by Gene Set Enrichment Analysis (GSEA) and essential genes in this enrichment. (E) MFAP2 knockdown affected the EGFR-AKT-STAT3 axis.
Techniques Used: Protein-Protein interactions, Knockdown
Related Articles
other:Article Title: Upregulation of PLOD2 expression promotes the development of psoriasis: A connection between keratinocytes and fibroblasts. Article Snippet: Psoriasis is a type of chronic inflammatory skin disease, with a rising incidence and high recurrence rate over the past decades.. The crosstalk between the epidermis and the dermis is crucial in psoriasis.. Here, we found that procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 (PLOD2), also known as lysyl hydroxylase 2 (LH2), may be a key component linking epidermal and dermal dysfunctions during the development of psoriasis. Incubation:Article Title: The Action Mechanism of Dendrobium spp. in Treating Dry Eye Disease Based on Network Pharmacology and In Vitro Experiments Article Snippet: .. Subsequently, the membranes were incubated overnight at 4 °C with the following primary antibodies from Cell Signaling Technology, Inc. (Danvers, MA, USA): Article Title: MFAP2 promotes metastasis and drug resistance by regulating epithelial-to-mesenchymal transition through EGFR signaling pathway in colorectal cancer cells Article Snippet: .. Following blocking with 5% non-fat milk in PBS with 0.02% Tween 20 detergent (PBST) at room temperature for 2 h, the membranes were incubated with primary antibodies, including MFAP2 (Solarbio, China), GAPDH (BBI Co., Ltd., China), epidermal growth factor receptor (EGFR; Proteintech, China), protein kinase B (AKT) (Proteintech), signal transducer and activator of transcription 3 (STAT3) (Proteintech), and vascular endothelial growth factor A (VEGFA) (Proteintech), Blocking Assay:Article Title: MFAP2 promotes metastasis and drug resistance by regulating epithelial-to-mesenchymal transition through EGFR signaling pathway in colorectal cancer cells Article Snippet: .. Following blocking with 5% non-fat milk in PBS with 0.02% Tween 20 detergent (PBST) at room temperature for 2 h, the membranes were incubated with primary antibodies, including MFAP2 (Solarbio, China), GAPDH (BBI Co., Ltd., China), epidermal growth factor receptor (EGFR; Proteintech, China), protein kinase B (AKT) (Proteintech), signal transducer and activator of transcription 3 (STAT3) (Proteintech), and vascular endothelial growth factor A (VEGFA) (Proteintech), |